Volume 19, Issue 4 (3-2022)
sjsph 2022, 19(4): 413-422 |
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Amirali A, Elikaei A, Mansour Ghanaie R, Boone I, Karimi A, Eckmanns T, et al . Seroepidemiology of SARS-CoV-2 Among Asymptomatic Children in Tehran. sjsph 2022; 19 (4) :413-422
URL: http://sjsph.tums.ac.ir/article-1-6089-en.html
URL: http://sjsph.tums.ac.ir/article-1-6089-en.html
Arezu Amirali1 
, Ameneh Elikaei2 , Roxana Mansour Ghanaie3 , Idesbald Boone4 , Abdollah Karimi5 , Tim Eckmanns4 , Andreas Lutz Jansen4 , Fatemeh Fallah5 , Noushin Marhamati6 , Niloofar Pashaei7 , Shahriar Janbazi8 , Ahmad Reza Shamshiri9 , Hamid Reza Baradaran10 , Mohammad Hossein Rostami11 , Masoud Alebouyeh * 12
, Ameneh Elikaei2 , Roxana Mansour Ghanaie3 , Idesbald Boone4 , Abdollah Karimi5 , Tim Eckmanns4 , Andreas Lutz Jansen4 , Fatemeh Fallah5 , Noushin Marhamati6 , Niloofar Pashaei7 , Shahriar Janbazi8 , Ahmad Reza Shamshiri9 , Hamid Reza Baradaran10 , Mohammad Hossein Rostami11 , Masoud Alebouyeh * 12
1- MSc. Department of Microbiology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran
2- Ph.D. Assistant Professor, Department of Microbiology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran
3- MD. Associate Professor, Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Ph.D. Researcher, Robert Koch Institute, Department of Infectious Disease Epidemiology, Berlin, Germany
5- MD. Professor, Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6- MD. Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
7- MD. Assistant Professor, Deputy of Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
8- Ph.D. Research Assistant Professor, Department of Health and Medical Medicine, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
9- MD. Assistant Professor, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
10- MD. Professor, Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
11- MSc. Strategy Director, Snapp, Iran Internet Group, Tehran, Iran
12- Ph.D. Assistant Professor, Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran ,masoud.alebouyeh@gmail.com
2- Ph.D. Assistant Professor, Department of Microbiology, Faculty of Biological Sciences, Alzahra University, Tehran, Iran
3- MD. Associate Professor, Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4- Ph.D. Researcher, Robert Koch Institute, Department of Infectious Disease Epidemiology, Berlin, Germany
5- MD. Professor, Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6- MD. Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
7- MD. Assistant Professor, Deputy of Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran
8- Ph.D. Research Assistant Professor, Department of Health and Medical Medicine, Faculty of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
9- MD. Assistant Professor, Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
10- MD. Professor, Department of Epidemiology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
11- MSc. Strategy Director, Snapp, Iran Internet Group, Tehran, Iran
12- Ph.D. Assistant Professor, Pediatric Infections Research Center, Research Institute for Children′s Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran ,
Abstract: (1357 Views)
Background and Aim: The objective of this study was to determine the seroepidemiological history of SARS-CoV-2 infection among asymptomatic children in Tehran.
Materials and Methods: Blood samples of children younger than 14 years old were collected during the period autumn-winter 2020 and spring 2021 and tested for SARS-CoV-2 IgG antibody using the EUROIMMUN ELISA kit. In addition, questionnaires were used to collect demographic and infection status information in the participants. Data were analyzed using the SPSS software.
Results: Out of the 1142 children collected from the children with no COVID-19 symptoms, 33.3% (381/1142) were found to have had a history of SARS-CoV-2. The positive samples in girls and boys were 34.1% and 33.03%, respectively. Analysis of the data showed no statistically significant differences between the infection rate on the one hand and age, family size, underlying diseases, gender or occupations of the family members on the other hand. In addition, the infection rate was significantly lower in autumn 2020 than in winter 2020 and spring 2021.
Conclusion: SARS-CoV-2 infection can occur in children with no clinical symptoms. In addition, the infection rate is in direct correlation with an increase in age of the children.
Materials and Methods: Blood samples of children younger than 14 years old were collected during the period autumn-winter 2020 and spring 2021 and tested for SARS-CoV-2 IgG antibody using the EUROIMMUN ELISA kit. In addition, questionnaires were used to collect demographic and infection status information in the participants. Data were analyzed using the SPSS software.
Results: Out of the 1142 children collected from the children with no COVID-19 symptoms, 33.3% (381/1142) were found to have had a history of SARS-CoV-2. The positive samples in girls and boys were 34.1% and 33.03%, respectively. Analysis of the data showed no statistically significant differences between the infection rate on the one hand and age, family size, underlying diseases, gender or occupations of the family members on the other hand. In addition, the infection rate was significantly lower in autumn 2020 than in winter 2020 and spring 2021.
Conclusion: SARS-CoV-2 infection can occur in children with no clinical symptoms. In addition, the infection rate is in direct correlation with an increase in age of the children.
Type of Study: Research |
Subject:
Public Health
Received: 2022/07/5 | Accepted: 2022/03/19 | Published: 2022/07/6
Received: 2022/07/5 | Accepted: 2022/03/19 | Published: 2022/07/6
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