Volume 3, Issue 2 (3 2005)
sjsph 2005, 3(2): 77-86 |
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Nahrevanian H, Assmar M, Ghorbani S M. A STUDY ON CRYPTOSPORIDIOSIS AMONG PATIENTS WITH ACQUIRED IMMUNODEFICIENCY IN THE GREAT TEHRAN. sjsph 2005; 3 (2) :77-86
URL: http://sjsph.tums.ac.ir/article-1-239-en.html
URL: http://sjsph.tums.ac.ir/article-1-239-en.html
Abstract: (10454 Views)
Cryptosporidiosis is a parasitic zoonosis prevalent all over the world and recognized as one
of the important causes of diarrhea in children and immunodeficient subjects. The
manifestations range from self-limited acute diarrhea in immunocompetent individuals to
fatal chronic diarrhea in immunocompromised patients. In this study, conducted in Greater
Tehran, 214 patients in 7 disease categories in 10 hospitals were investigated. Samples
were collected from both patients with immune deficiency symptoms (Test group) and
those with an intact immune system (Control group).
Overall, 22.4% of patients had diarrhea and 77.6% had stools with a normal consistency.
1.4% of immunocompromised patients and 6.3% of those with diarrhea were found to
harbor Cryptosporidium infections. These Cryptosporidium-positive cases included one
patient with AML and two AIDS patients. The incidence rate of infection in AML and
AIDS patients who had diarrhea was 11.1% and 33.4%, respectively. While the infection is
usually self-limited in immunocompetent subjects, it could be fatal in immunodeficiency
states. Therefore attention must be paid to effective disease prevention in
immunocompromised subjects.
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