Volume 16, Issue 4 (3-2019)
sjsph 2019, 16(4): 363-372 |
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Peikani S, Nasiri N, Yaghoobi H, Bastam D, Doost Mohammadi F, Vahedian Shahroudi M. The Prevalence of Congenital Hypothyroidism in Newborns Referred to Shahid Ghodsi Health Center, Mashhad . sjsph 2019; 16 (4) :363-372
URL: http://sjsph.tums.ac.ir/article-1-5706-en.html
URL: http://sjsph.tums.ac.ir/article-1-5706-en.html
Sahar Peikani1 
, Naser Nasiri2 , Halimeh Yaghoobi * 3, Dayoush Bastam4 , Fatemeh Doost Mohammadi4 , Mohammad Vahedian Shahroudi5
, Naser Nasiri2 , Halimeh Yaghoobi * 3, Dayoush Bastam4 , Fatemeh Doost Mohammadi4 , Mohammad Vahedian Shahroudi5
1- BSc. Comprehensive Service Center Shahid Ghodsi, Mashhad University of Medical Sciences, Mashhad, Iran
2- MSc. Instructor, Department of Public Health, School of Public Health, Jiroft University of Medical Sciences, Jiroft, Iran
3- MSc. Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran ,Lemen_2012@yahoo.com
4- MSc. Student, Department of Epidemiology and Biostatistics, Medical School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
5- Ph.D. Assistant Professor, Department of Health Education and Health Promotion, Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
2- MSc. Instructor, Department of Public Health, School of Public Health, Jiroft University of Medical Sciences, Jiroft, Iran
3- MSc. Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran ,
4- MSc. Student, Department of Epidemiology and Biostatistics, Medical School, Rafsanjan University of Medical Sciences, Rafsanjan, Iran
5- Ph.D. Assistant Professor, Department of Health Education and Health Promotion, Social Determinants of Health Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
Abstract: (3320 Views)
Background and Aim: Congenital hypothyroidism is the most common metabolic disease and endocrine disorder in children and a major cause of mental retardation, which can be prevented only through early diagnosis and treatment. This study aimed to determine the prevalence of congenital hypothyroidism in newborns referred to Shahid-Ghodsi Health Center in Mashhad, Iran.
Materials and Methods: This cross-sectional study, including 4484 newborns referred to Shahid-Ghodsi Health Center for congenital hypothyroidism screening, was conducted during the first six months of 2015. Data were collected from the screening forms and analyzed using the statistical software SPSS 21, the tests being the two-sample T-test, analysis of variance, Chi-square and Fisher's exact tests; in all the tests the significance level was 5%.
Results: Of the 4484 neonates screened, 51% and 48% were males and females, respectively. The recall rate was estimated to be 2.6% and prevalence of the disease 1 in 370 neonates. There were statistically significant associations between hypothyroidism on the one hand and birthweight, type of feeding (nutrition), primary and serum TSH levels of the neonate on the other.
Conclusion: Based on the findings, the prevalence of congenital hypothyroidism in Mashhad is significantly higher than that national and global averages. It is essential to conduct more comprehensive research to determine the associated factors and design suitable interventions in order to prevent the disease.
Materials and Methods: This cross-sectional study, including 4484 newborns referred to Shahid-Ghodsi Health Center for congenital hypothyroidism screening, was conducted during the first six months of 2015. Data were collected from the screening forms and analyzed using the statistical software SPSS 21, the tests being the two-sample T-test, analysis of variance, Chi-square and Fisher's exact tests; in all the tests the significance level was 5%.
Results: Of the 4484 neonates screened, 51% and 48% were males and females, respectively. The recall rate was estimated to be 2.6% and prevalence of the disease 1 in 370 neonates. There were statistically significant associations between hypothyroidism on the one hand and birthweight, type of feeding (nutrition), primary and serum TSH levels of the neonate on the other.
Conclusion: Based on the findings, the prevalence of congenital hypothyroidism in Mashhad is significantly higher than that national and global averages. It is essential to conduct more comprehensive research to determine the associated factors and design suitable interventions in order to prevent the disease.
Type of Study: Research |
Subject:
Public Health
Received: 2019/03/13 | Accepted: 2019/03/13 | Published: 2019/03/13
Received: 2019/03/13 | Accepted: 2019/03/13 | Published: 2019/03/13
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