Volume 2, Issue 2 (4 2004)                   sjsph 2004, 2(2): 35-42 | Back to browse issues page

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Yahya pour M, Razjoo F, Karimi G. EFFECT OF HEPATITIS B VACCINATION ON HBsAg STATUS IN BLOOD DONORS. sjsph. 2004; 2 (2) :35-42
URL: http://sjsph.tums.ac.ir/article-1-267-en.html
Abstract:   (5706 Views)

The purpose of this study was to evaluate the influence of hepatitis B vaccination on the results of surface antigen tests in blood donors. In this research, eighteen non-immunized volunteers (ten male, eight female) aged 21 to 58 years received 20 ug of the recombinant B vaccine (Heberbiovac-HB) intramuscularly. Blood samples were drawn from all volunteers before the first vaccine dose (day 0) and on days 1,2,3 and 7 after vaccination. HBSAg assessment was done by six different kits (Behring, organon, Diasorin, Equipar, Trinity, Radim ). In this study, seven (39 %) of the eighteen volunteers showed a positive HBSAg reaction, confirmed by the duplicate samples. The most positive reactions were obtained by trinity kit on day 5 and 7. We conclude that individuals recently vaccinated against hepatitis B may have positive tests for HBSAg and it is recommended that such persons defer all blood donations for at least 7 days.

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Type of Study: Research | Subject: General
Published: 2013/07/10

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